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Collagen(/ˈkɒlədʒən/) is the main structural proteinin the extracellular matrixof a body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals. [1]25% to 35% of a mammalian body's protein content is collagen.
Collagen VI (ColVI) is a type of collagen primarily associated with the extracellular matrix of skeletal muscle. [1] ColVI maintains regularity in muscle function and stabilizes the cell membrane. [2] It is synthesized by a complex, multistep pathway that leads to the formation of a unique network of linked microfilaments located in the ...
Type IV collagen. Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, collagen IV lacks the regular glycine in every third residue necessary for the ...
TH. H2.00.03.0.02001. Anatomical terms of microanatomy. [ edit on Wikidata] In biology, the extracellular matrix (ECM), [ 1 ][ 2 ] also called intercellular matrix (ICM), is a network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical ...
Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue. [ 1 ] It develops mostly from the mesenchyme, derived from the mesoderm, the middle embryonic germ layer. [ 2 ] Connective tissue is found in between other tissues everywhere in the body, including the nervous ...
On the other hand, the strict meaning of "tissue culture" refers to the culturing of tissue pieces, i.e. explant culture. Tissue culture is an important tool for the study of the biology of cells from multicellular organisms. It provides an in vitro model of the tissue in a well defined environment which can be easily manipulated and analysed ...
The basement membrane, also known as base membrane, is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. [1][2] The basement membrane sits between epithelial tissues including mesothelium and endothelium, and the underlying connective tissue. [3][4]
Cartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, [ 1 ] and is a structural component of many body parts including the rib ...