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Many causes of autism, including environmental and genetic factors, have been recognized or proposed, but understanding of the theory of causation of autism is incomplete. [1] Attempts have been made to incorporate the known genetic and environmental causes into a comprehensive causative framework. [ 2 ]
Some are more comprehensive, such as the Pathogenetic Triad, which proposes and operationalizes three core features (an autistic personality, cognitive compensation, neuropathological burden) that interact to cause autism, [217] and the Intense World Theory, which explains autism through a hyper-active neurobiology that leads to an increased ...
The history of Autism spans over a century; [ 1 ] Autism has been subject to varying treatments, being pathologized or being viewed as a beneficial part of human neurodiversity. [ 2 ] The understanding of Autism has been shaped by cultural, scientific, and societal factors, and its perception and treatment change over time as scientific ...
Epidemiology of autism. The epidemiology of autism is the study of the incidence and distribution of autism spectrum disorders (ASD). A 2022 systematic review of global prevalence of autism spectrum disorders found a median prevalence of 1% in children in studies published from 2012 to 2021, with a trend of increasing prevalence over time.
Pathophysiology of autism. The pathophysiology of autism is the study of the physiological processes that cause or are otherwise associated with autism spectrum disorders. Autism's symptoms result from maturation-related changes in various systems of the brain. [1] How autism occurs is not yet well understood.
The heritability of autism is the proportion of differences in expression of autism that can be explained by genetic variation; if the heritability of a condition is high, then the condition is considered to be primarily genetic. Autism has a strong genetic basis. Although the genetics of autism are complex, autism spectrum disorder (ASD) is ...
Asperger syndrome (AS), also known as Asperger's syndrome or Asperger's, is a diagnosis formerly used to describe a neurodevelopmental condition characterized by significant difficulties in social interaction and nonverbal communication, along with restricted, repetitive patterns of behavior and interests. [ 5 ]
Classic autism. Classic autism, also known as childhood autism, autistic disorder, (early) infantile autism, infantile psychosis, Kanner's autism, Kanner's syndrome, or (formerly) just autism, is a neurodevelopmental condition first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction ...