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2. Goodman & Gilman's The Pharmacological Basis of Therapeutics

   en.wikipedia.org/wiki/Goodman_&_Gilman's_The...

   Louis S. Goodman. Goodman & Gilman's The Pharmacological Basis of Therapeutics, commonly referred to as the Blue Bible or Goodman & Gilman, is a textbook of pharmacology originally authored by Louis S. Goodman and Alfred Gilman. First published in 1941, the book is in its 14th edition (as of 2022), and has the reputation of being the "bible of ...

3. Selective estrogen receptor modulator - Wikipedia

   en.wikipedia.org/wiki/Selective_estrogen...

   Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), [ 1 ][ 2 ] are a class of drugs that act on estrogen receptors (ERs). [ 3 ] Compared to pure ER agonists – antagonists (e.g., full agonists and silent antagonists), SERMs are more tissue-specific, allowing them to selectively inhibit ...

4. Pharmacodynamics - Wikipedia

   en.wikipedia.org/wiki/Pharmacodynamics

   Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology ...

5. Cephalosporin - Wikipedia

   en.wikipedia.org/wiki/Cephalosporin

   Cephalosporins are bactericidal and, like other β-lactam antibiotics, disrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by penicillin-binding proteins (PBPs).

6. Therapeutic drug monitoring - Wikipedia

   en.wikipedia.org/wiki/Therapeutic_drug_monitoring

   Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range, i.e. drugs that can easily be under- or overdosed. [ 1 ] TDM aimed at improving patient care by individually adjusting the ...

7. Clinical pharmacology - Wikipedia

   en.wikipedia.org/wiki/Clinical_pharmacology

   Clinical pharmacology. Clinical pharmacology is "that discipline that teaches, does research, frames policy, gives information and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice". [1][2] Clinical pharmacology is inherently a translational discipline underpinned by the basic ...

8. Pharmacokinetics - Wikipedia

   en.wikipedia.org/wiki/Pharmacokinetics

   Pharmacokinetics. A graph depicting a typical time course of drug plasma concentration over 96 hours, with oral administrations every 24 hours. The main pharmacokinetic metrics are annotated. Steady state is reached after about 5 × 12 = 60 hours. Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion ...

9. Drug tolerance - Wikipedia

   en.wikipedia.org/wiki/Drug_tolerance

   t. e. Drug tolerance or drug insensitivity is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use. Increasing its dosage may re-amplify the drug's effects; however, this may accelerate tolerance, further reducing the drug's effects. Drug tolerance is indicative of drug use but is not necessarily ...