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Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
Vitamin D toxicity, or hypervitaminosis D, is the toxic state of an excess of vitamin D. The normal range for blood concentration of 25-hydroxyvitamin D in adults is 20 to 50 nanograms per milliliter (ng/mL).
Vitamin D is a group of structurally related, fat-soluble compounds responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [1] [2] In humans, the most important compounds within this group are vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol). [2] [3]
With the vitamin D deficiency resurfacing the nutrient reference value guidelines were established, in turn creating the dietary vitamin D recommendations. [2] The dietary vitamin D guidelines are assuming limited exposure to UVB sunlight are: Infants, Children and Adults < 50 years: 5 μg/day (200 IU/day)
The Dietary Guidelines for Americans (2020–2025) outline four principles for healthy eating habits: Dietary patterns should shift with each stage of life; Enjoy nutrient-rich food and beverages that adhere to one's budget and reflect one's personal preferences and cultural traditions; Meet food group needs and stay within calorie limits
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The Dietary Reference Intake (DRI) is a system of nutrition recommendations from the National Academy of Medicine (NAM) [a] of the National Academies (United States). [1] It was introduced in 1997 in order to broaden the existing guidelines known as Recommended Dietary Allowances (RDAs, see below).
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [3] to prevent and treat vitamin D deficiency [4] due to poor absorption by the intestines or liver disease. [5]
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