Search results
Results from the WOW.Com Content Network
The psychoactive effects of cannabis, known as a "high", are subjective and vary among persons and the method of use. When THC enters the blood stream and reaches the brain, it binds to cannabinoid receptors. The endogenous ligand of these receptors is anandamide, the effects of which THC emulates.
More and more states are legalizing marijuana for medical and/or recreational use. High blood pressure is a major risk factor for heart attack and stroke. Stage 1 hypertension is defined as a ...
Cannabinoid receptor type 1 (CB 1) receptors are thought to be one of the most widely expressed G αi protein-coupled receptors in the brain. One mechanism through which they function is endocannabinoid-mediated depolarization-induced suppression of inhibition , a very common form of retrograde signaling , in which the depolarization of a ...
3D model of 2-Arachidonoylglycerol, an endocannaboid. The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous system (including the brain) and peripheral nervous system.
A growing body of research and numerous anecdotal reports link cannabis with several health benefits.
Weed affects your ability to make decisions, control emotions, remember important data, plan, organize and solve problems, a new study found, and that impact may last well past your initial high.
For instance, when the release of the inhibitory transmitter GABA is reduced, the net effect is an increase in the excitability of the endocannabinoid-releasing cell. On the converse, when release of the excitatory neurotransmitter glutamate is reduced, the net effect is a decrease in the excitability of the endocannabinoid-releasing cell.
Via CB 1 receptor activation, THC indirectly increases dopamine release and produces psychotropic effects. [129] CBD also acts as an allosteric modulator of the μ-and δ-opioid receptors. [130] THC also potentiates the effects of the glycine receptors. [131] It is unknown if or how these actions contribute to the effects of cannabis. [132]