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A chemical restraint is a form of medical restraint in which a drug is used to restrict the freedom or movement of a patient or in some cases to sedate the patient. Chemical restraint is used in emergency, acute, and psychiatric settings to perform surgery or to reduce agitation, aggression or violent behaviours; [a] it may also be used to control or punish unruly behaviours. [2]
Chemical restraint, such as forcible injection with the antipsychotic haloperidol or benzodiazepine sedative midazolam, may be used to sedate a patient who is agitated. [ 36 ] : 624 [ 37 ] : 152 In some countries, antipsychotics and sedatives can be forcibly administered to those who are committed , using intramuscular depot injection . [ 38 ]
In the U.S. in the late 2010s and into the 2020s (so far), restraint of psychiatric patients and/or people with mental disorders (for all purpose other than very temporarily if another person would be in danger) has come under heavy fire from many professionals (such as those in the Therapist Neurodiversity Collective) and human rights groups (such as Alliance Against Seclusion and Restraint ...
Dossier evaluation is conducted by authorities to examine proposals for testing to ensure that unnecessary animal tests and costs are avoided, and to check the compliance of registration dossier with the registration requirements. Chemical companies failed to provide "important safety information" in nearly three quarters (74% or 211 of 286) of ...
Pharmaceuticals may also be described as "specialty", independent of other classifications, which is an ill-defined class of drugs that might be difficult to administer, require special handling during administration, require patient monitoring during and immediately after administration, have particular regulatory requirements restricting ...
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Process Safety Management of Highly Hazardous Chemicals is a regulation promulgated by the U.S. Occupational Safety and Health Administration (OSHA). [1] It defines and regulates a process safety management (PSM) program for plants using, storing, manufacturing, handling or carrying out on-site movement of hazardous materials above defined amount thresholds.
By extension, this often means regulations, standards, and/or guidelines are in place to better ensure analyses are approved and reported correctly. For example, regulations, standards, and/or guidelines affect COA use in agriculture, [2] [3] chemical, [4] [5] clinical research, [6] [7] food and beverage, [8] [9] and pharmaceutical [6] [7] [10 ...