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Medications that interfere with potassium levels, such as diuretics; Poisons linked to rhabdomyolysis are heavy metals and venom from insects or snakes. [4] Hemlock may cause rhabdomyolysis, either directly or after eating quail that have fed on it. [4] [12] Fungi such as Russula subnigricans and Tricholoma equestre are known to cause ...
Nephrotoxicity: [14] acute kidney injury from rhabdomyolysis; Also, myopathy and rhabdomyolysis have been reported in patients simultaneously taking statins, [15] but whether this is due entirely to the statin or whether daptomycin potentiates this effect is unknown. Due to the limited data available, the manufacturer recommends that statins be ...
A noted drug interaction involves erythromycin and simvastatin, resulting in increased simvastatin levels and the potential for rhabdomyolysis. Another group of CYP3A4 substrates are drugs used for migraine such as ergotamine and dihydroergotamine; their adverse effects may be more pronounced if erythromycin is associated. [23]
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Effective for gram-positive, gram-negative, anaerobic, and against multi-antibiotic resistant bacteria (such as Staphylococcus aureus [MRSA] and Acinetobacter baumannii), but not effective for Pseudomonas spp. and Proteus spp. Teeth discoloration and same side effects as tetracycline. Not to be given to children and pregnant or lactating women.
Children appear to be at a high risk for cardiopulmonary arrest. A toxic dose for children of more than 1.8 mg/kg has been reported. A 3-year-old child died 18 hours after ingesting 1,000 mg doxylamine succinate. [5] Rarely, an overdose results in rhabdomyolysis and acute kidney injury. [36]
Penicillins are a widely used group of medications that are effective for the treatment of a wide variety of bacterial infections in human adults and children as well as other species. Some side effects are predictable, of which some are common but not serious, some are uncommon and serious and others are rare. [ 2 ]