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A contrast is defined as the sum of each group mean multiplied by a coefficient for each group (i.e., a signed number, c j). [10] In equation form, = ¯ + ¯ + + ¯ ¯, where L is the weighted sum of group means, the c j coefficients represent the assigned weights of the means (these must sum to 0 for orthogonal contrasts), and ¯ j represents the group means. [8]
In mathematics, the difference of two squares is a squared (multiplied by itself) number subtracted from another squared number. Every difference of squares may be factored according to the identity a 2 − b 2 = ( a + b ) ( a − b ) {\displaystyle a^{2}-b^{2}=(a+b)(a-b)}
A different set of techniques have been developed for "large-scale multiple testing", in which thousands or even greater numbers of tests are performed. For example, in genomics, when using technologies such as microarrays, expression levels of tens of thousands of genes can be measured, and genotypes for millions of genetic markers can be measured
There are several different notations used to represent different kinds of inequalities: The notation a < b means that a is less than b. The notation a > b means that a is greater than b. In either case, a is not equal to b. These relations are known as strict inequalities, [1] meaning that a is strictly less than or strictly greater than b ...
The system + =, + = has exactly one solution: x = 1, y = 2 The nonlinear system + =, + = has the two solutions (x, y) = (1, 0) and (x, y) = (0, 1), while + + =, + + =, + + = has an infinite number of solutions because the third equation is the first equation plus twice the second one and hence contains no independent information; thus any value of z can be chosen and values of x and y can be ...
By contrast, simple subtraction is not non-negative or commutative, but it does obey the second and fourth properties above, since = if and only if =, and = + (). The absolute difference is used to define other quantities including the relative difference , the L 1 norm used in taxicab geometry , and graceful labelings in graph theory .
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