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The Hill equation reflects the occupancy of macromolecules: the fraction that is saturated or bound by the ligand. [1] [2] [nb 1] This equation is formally equivalent to the Langmuir isotherm. [3] Conversely, the Hill equation proper reflects the cellular or tissue response to the ligand: the physiological output of the system, such as muscle ...
However, a series of publications by Popova and Sel'kov [2] derived the MWC rate equation for the reversible, multi-substrate, multi-product reaction. The same problem applies to the classic Hill equation which is almost always shown in an irreversible form. Hofmeyr and Cornish-Bowden first published the reversible form of the Hill equation. [1]
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In this paper, Hill's first publication, he derived both the equilibrium form of the Langmuir equation, and also the exponential approach to equilibrium. The paper, written under the supervision of John Newport Langley , is a landmark in the history of receptor theory, because the context for the derivation was the binding of nicotine and ...
Download QR code; Print/export Download as PDF; Printable version; In other projects ... move to sidebar hide. Hill equation may refer to Hill equation (biochemistry) ...
Hill's finding was that the origin of oxygen in photosynthesis is water (H 2 O) not carbon dioxide (CO 2) as previously believed. Hill's observation of chloroplasts in dark conditions and in the absence of CO 2, showed that the artificial electron acceptor was oxidized but not reduced, terminating the process, but without production of oxygen ...
Hill's spherical vortex is an exact solution of the Euler equations that is commonly used to model a vortex ring. The solution is also used to model the velocity distribution inside a spherical drop of one fluid moving at a constant velocity through another fluid at small Reynolds number. [ 1 ]