Search results
Results from the WOW.Com Content Network
Tumors may be graded on four-tier, three-tier, or two-tier scales, depending on the institution and the tumor type. The histologic tumor grade score along with the metastatic (whole-body-level cancer-spread) staging are used to evaluate each specific cancer patient, develop their individual treatment strategy and to predict their prognosis.
For each participant, it assumes that there exist a true score and it need to be obtained score (X) has to be as close to it as possible. [2] [4] The closeness of X has with T is expressed in terms of ratability of the obtained score. The reliability in terms of classical test procedure is correlation between true score and obtained score.
The Ki-67 score closely correlates with other proliferation markers, and has been shown to have prognostic and predictive value for many different tumor types. [9] Similarly, proliferating cell nuclear antigen (PCNA) is a protein associated with cell proliferation that is upregulated in proliferating cells, making it another useful antigen for ...
Psycho-oncology deals with psychological reactions to the experience of cancer, the behavioral component of coping with cancer as well as health behavior change including preventive medicine, and social factors that are associated with diagnosis and treatment of cancer, including communication with providers and loved ones and social support.
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
It is the proportion of individuals in a population who have a certain characteristic or trait. For example, if 1% of the population were medical professionals, and remaining 99% were not medical professionals, then the base rate of medical professionals is 1%. The method for integrating base rates and featural evidence is given by Bayes' rule.
Therefore, the utilization of such techniques for objective tumor response should be restricted to validation purposes in specialized centers. However, such techniques can be useful in confirming complete pathological response when biopsies are obtained. Tumor markers alone cannot be used to assess response.