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The same clinical decisions that would influence the choice between stand-alone CT or MR imaging would also determine areas where PET-CT or PET-MR would be preferred. [14] For example, one advantage of MRI compared to CT is its superior soft tissue contrast, while CT has the advantage of being much faster than MRI.
Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, [4] discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow ( hemodynamic response ) related to energy use by brain ...
Functional connectivity analyses allow the characterization of interregional neural interactions during particular cognitive or motor tasks or merely from spontaneous activity during rest. FMRI and PET enable creation of functional connectivity maps of distinct spatial distributions of temporally correlated brain regions called functional networks.
Brain positron emission tomography is a form of positron emission tomography (PET) that is used to measure brain metabolism and the distribution of exogenous radiolabeled chemical agents throughout the brain. PET measures emissions from radioactively labeled metabolically active chemicals that have been injected into the bloodstream.
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to form images of the organs in the body.
PET, MRI, and overlaid images of a human brain. Positron emission tomography (PET) is a nuclear medicine imaging technique which produces a three-dimensional image or picture of functional processes in the body. The theory behind PET is simple enough. First a molecule is tagged with a positron emitting isotope.
PET radioisotopes have limited exposure time in the body as they commonly have very short half-lives (~2 hours) and decay rapidly. [38] Currently, fMRI is a preferred method of imaging brain activity compared to PET, since it does not involve radiation, has a higher temporal resolution than PET, and is more readily available in most medical ...
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