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RXR/RAR heterodimers transmit retinoid signals in diverse ways to control the expression of networks of retinoic acid (RA) target genes. This process plays a crucial role in shaping both the axial and limb patterning during early embryo development, as well as influencing various aspects of organ formation in later stages of development.
The RA-15 was developed in 1948 as a higher-powered successor to the Adam RA-14 Loisirs, utilising a number of refinements including a plywood-covered fuselage and an enlarged rudder. It was a side-by-side two-seater with dual controls, wooden construction and a fabric-covered two-spar wing which folded for storage in hangars.