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Transcatheter aortic valve implantation (TAVI) is the implantation of the aortic valve of the heart through the blood vessels without actual removal of the native valve (as opposed to the aortic valve replacement by open heart surgery, surgical aortic valve replacement, AVR). The first TAVI was performed on 16 April 2002 by Alain Cribier, which ...
The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.
The GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) is a method of assessing the certainty in evidence (also known as quality of evidence or confidence in effect estimates) and the strength of recommendations in health care. [1] It provides a structured and transparent evaluation of the importance of outcomes ...
josephbavaria.com. Joseph E. Bavaria, M.D., FACS, FRCS (Edin) ad hom, (born 1957) is an American cardiothoracic surgeon [6] a professor of surgery at the University of Pennsylvania and Director of its Thoracic Aortic Surgery Program. [b][3] Bavaria is known as a leading figure in clinical trials for catheter-based aortic valve replacement (TAVR ...
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research.Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and treatment of cancer.
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery ...
Oncogenomics. Oncogenomics is a sub-field of genomics that characterizes cancer -associated genes. It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.
Researchers are designing ‘dancing’ molecule meant to make it easier for cartilage damaged by osteoarthritis to regenerate. Image credit: adamkaz/Getty Images. Osteoarthritis is a common and ...