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Dextromethorphan (DXM), sold under the trade name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] It affects serotonin, norepinephrine, NMDA, and sigma-1 receptors in the brain, all of which have been implicated in the pathophysiology of depression.
Cloperastine (INN) or cloperastin, in the forms of cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate, is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. [1][2][3] It was first introduced in 1972 in Japan, and then in ...
Benzonatate is a prescription non-opioid alternative for the symptomatic relief of cough.[7] [10] It has been found to improve cough associated with a variety of respiratory conditions including asthma, bronchitis, pneumonia, tuberculosis, pneumothorax, opioid-resistant cough in lung cancer, and emphysema.
Clofedanol. Clofedanol (INN) or chlophedianol (BAN), sold under the brand name Ninjacof among others, is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic, antispasmodic, and antihistamine properties, [1] and may have anticholinergic effects at high doses. [2]
Guaifenesin, also known as glyceryl guaiacolate, is an expectorant medication taken by mouth and marketed as an aid to eliminate sputum from the respiratory tract. Chemically, it is an ether of guaiacol and glycerine. It may be used in combination with other medications. [4]
Corex is not generally a fatal drug substitute, unless taken in extremely high quantities. However, many side effects are common. Corex is known to cause short term memory loss, sleeplessness, tremors and spasms. Muscular pains and dehydration are other common side-effects. Long term abuse leads to serious kidney damage or constipation.
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for h igh b lood p ressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer ...
Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup. It was patented in 1966 and came into medical use in 1979. [1]