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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Congenital syphilis. Notched incisors known as Hutchinson's teeth which are characteristic of congenital syphilis. Specialty. Infectious diseases. Symptoms. Rash, fever, large liver and spleen, skeletal abnormalities [1] Usual onset. Unborn baby, newborn baby or later [1] Duration.
The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...
Neurosyphilis is the infection of the central nervous system in a patient with syphilis. In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients. [citation needed] Meningitis is the most common neurological presentation in early syphilis. Tertiary syphilis symptoms are exclusively ...
350–500. >500. Syphilis is a bacterial infection transmitted by sexual contact [2] and is believed to have infected 12 million people in 1999 with greater than 90% of cases in the developing world. [3] It affects between 700,000 and 1.6 million pregnancies a year, resulting in spontaneous abortions, stillbirths, and congenital syphilis. [4]
Meningeal syphilis. Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum, a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if ...
The Tuskegee Study of Untreated Syphilis in the Negro Male[1] (informally referred to as the Tuskegee Experiment or Tuskegee Syphilis Study) was a study conducted between 1932 and 1972 by the United States Public Health Service (PHS) and the Centers for Disease Control and Prevention (CDC) on a group of nearly 400 African American men with ...
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
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