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Urology addresses diseases of kidney (and urinary tract) anatomy: these include cancer, renal cysts, kidney stones and ureteral stones, and urinary tract obstruction. [ 7 ] The word “ renal ” is an adjective meaning “relating to the kidneys”, and its roots are French or late Latin.
Mammalian kidneys are susceptible to ischemic injury because mammals lack a renal-portal system, and as a result, vascular vasoconstriction in the glomeruli can lead to decreased blood supply to the entire kidney. The kidneys are susceptible to toxic injury, since toxins are reabsorbed in the tubules along with most of the filtered substances. [47]
This is an accepted version of this page This is the latest accepted revision, reviewed on 5 February 2025. This article is about the human urinary system. For urinary systems of other vertebrates, see Urinary systems of birds, urinary systems of reptiles, and urinary systems of amphibians. Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra Urinary system 1 ...
The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts: a renal corpuscle, which is the initial filtering component, and; a renal tubule that processes and carries away the filtered fluid. [4]: 1024
However, this model is greatly simplified for clarity and symmetry. Some of the other paths and complications are described at the bottom of the table. The interlobar artery and vein (not to be confused with interlobular) are between two renal lobes, also known as the renal column (cortex region between two pyramids).
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
Unlike mammals, the kidneys of reptiles do not have a clear distinction between cortex and medulla. [43] The kidneys lack the loop of Henle, have fewer nephrons (from about 3,000 to 30,000), and cannot produce hypertonic urine. [3] [21] Nitrogenous waste products excreted by the kidneys may include uric acid, urea and ammonia. [55]
The glomerulus (pl.: glomeruli) is a network of small blood vessels (capillaries) known as a tuft, located at the beginning of a nephron in the kidney. Each of the two kidneys contains about one million nephrons. The tuft is structurally supported by the mesangium (the space between the blood vessels), composed of intraglomerular mesangial cells.
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