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An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient, [1] encompassing compounds, peptides and low-molecular-weight proteins (e.g., insulin, hormones, cytokines), as well as complex biological products, such as those used for gene therapy. [2]
Neluxicapone (INN Tooltip International Nonproprietary Name) is a catechol O-methyltransferase (COMT) inhibitor which has not been marketed as of 2024. [1] [2] [3] The drug is a nitrocatechol and is structurally related to other catechol COMT inhibitors like entacapone, tolcapone, and nebicapone.
The World Health Organization (WHO) introduced the system of International Nonproprietary Names in 1950, with the first INN list being published three years later. The stem -mab for monoclonal antibodies was proposed around 1990, and the current system with target and source substems was developed between 1991 and 1993. Due to the collaboration ...
The article title and the first name to mention in the lead should be the International Nonproprietary Name (INN) of the drug; see below. The British Approved Name (BAN) or United States Adopted Name (USAN) variant may also be mentioned. The initial brand name(s) follows, in parentheses. All drug names should be in boldface per WP:BOLDTITLE.
Vafidemstat (INN Tooltip International Nonproprietary Name; developmental code name ORY-2001) is a dual inhibitor of the enzymes lysine-specific demethylase 1 (LSD1; KDM1A) and monoamine oxidase B (MAO-B) which is under development for the treatment of a variety of medical conditions, including aggression, Alzheimer's disease, borderline personality disorder, multiple sclerosis, acute ...
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Drugs—The international nonproprietary name (INN). Most biologics, including vaccines, do not have INN or other generic names, so the brand name is used instead. Nonproprietary names are common nouns and hence should be lower case except in titles, the beginning of sentences, and in other situations that require capitalization. [5]
Serplulimab is the International nonproprietary name. [6] References ... "First-line serplulimab in metastatic colorectal cancer: Phase 2 results of a randomized ...