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The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. [2] It consists of the cerebral peduncles , tegmentum , and tectum . It is functionally associated with vision, hearing, motor control, sleep and wakefulness, arousal ( alertness ), and temperature regulation.
Anatomically, as the name suggests, the MLR is located in the mesencephalon (or midbrain), ventral to the inferior colliculus and near the cuneiform nucleus. [6] Although identifying the exact anatomical substrates of the MLR has been subject to considerable debate, the pedunculopontine nucleus (PPN), cuneiform nucleus, and midbrain ...
The mesencephalon is the second of the three primary vesicles, and does not further differentiate into a secondary brain vesicle. This will become the midbrain. The third primary vesicle, the rhombencephalon (hindbrain) will further differentiate into two secondary vesicles, the metencephalon and the myelencephalon.
Vesicles of the forebrain (prosencephalon), the midbrain (mesencephalon), and hindbrain (rhombencephalon) are the three primary brain vesicles during the early development of the nervous system. At the five-vesicle stage, the forebrain separates into the diencephalon ( thalamus , hypothalamus , subthalamus , and epithalamus ) and the ...
It forms the floor of the midbrain (mesencephalon) whereas the tectum forms the ceiling. [2] It is a multisynaptic network of neurons that is involved in many subconscious homeostatic and reflexive pathways. It is a motor center that relays inhibitory signals to the thalamus and basal nuclei preventing unwanted body movement. [citation needed]
Caudally, it is continuous with the fourth ventricle at the junction of the mesencephalon and pons. [3] The midbrain tegmentum is situated anteriorly to the cerebral aqueduct. [3] The portion of the tegmentum posterior to the aqueduct is the tectum. [1] The superior and inferior colliculi that make up the corpora quadrigemina are situated ...
These swellings are known as the primary brain vesicles and represent the beginnings of the forebrain (prosencephalon), midbrain (mesencephalon), and hindbrain (rhombencephalon). [65] [66] Neural crest cells (derived from the ectoderm) populate the lateral edges of the plate at the neural folds.
Initially there are three primary brain vesicles: prosencephalon (i.e. forebrain), mesencephalon (i.e. midbrain) and rhombencephalon (i.e. hindbrain). These develop into five secondary brain vesicles – the prosencephalon is subdivided into the telencephalon and diencephalon, and the rhombencephalon into the metencephalon and myelencephalon.