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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
Fumonisins were the most recent mycotoxin found to affect humans and animals negatively. The most produced toxin for this group of fungi is fumonisin B1. [2] Studies have shown that it can cause diseases such as equine leukoencephalomalacia in horses, hydrothorax and porcine pulmonary edema in swine, and it can negatively affect the immune system.
Naturally occurring phenethylamines are organic compounds which may be thought of as being derived from phenethylamine itself that are found in living organisms. Tyramine is a phenethylamine that occurs widely in plants [ 1 ] and animals , and is metabolized by various enzymes , including monoamine oxidases .
Phenolic acids can be found in mushroom basidiomycetes species. [45] For example, protocatechuic acid and pyrocatechol are found in Agaricus bisporus [46] as well as other phenylated substances like phenylacetic and phenylpyruvic acids. Other compounds like atromentin and thelephoric acid can also be isolated from fungi in the Agaricomycetes class.
The compounds of these secondary metabolites (As seen in Figure 1) are found in over 2000 plant species. Its structure allows the release of cyanide, a poison produced by certain bacteria, fungi, and algae that is found in numerous plants. Animals and humans possess the ability to detoxify cyanide from their systems naturally.
[1] [2] The production of defensive chemicals occurs in plants, fungi, and bacteria, as well as invertebrate and vertebrate animals. [3] [4] The class of chemicals produced by organisms that are considered defensive may be considered in a strict sense to only apply to those aiding an organism in escaping herbivory or predation. [1]
The ecological roles of these fungi are diverse and still poorly understood. These endophyte plant interactions are widespread and have been found in nearly all land plants and ecosystems. [43] Many non-clavicipitaceous endophytes have the ability to switch between endophytic behavior and free-living lifestyles.
Pathogenic fungi are fungi that cause disease in humans or other organisms. Although fungi are eukaryotic , many pathogenic fungi are microorganisms . [ 1 ] Approximately 300 fungi are known to be pathogenic to humans; [ 2 ] their study is called " medical mycology ".