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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
If they’re stored in optimal conditions, you can get the most bang for your buck. Best case scenario, the average shelf-life of vitamins is two years, Davis-Cadogan adds. There are some vitamins ...
Defrosting a freezer with an improvised water collection method. In refrigerators, defrosting (or thawing) is the removal of frost and ice. A defrosting procedure is generally performed periodically on refrigerators and freezers to maintain their operating efficiency.
The hit movie "Wicked" is set to be available for purchase on streaming platforms this week after opening as the largest stage musical adaptation of all time.. The film starring singer Ariana ...
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Store leafy greens in the crisper drawer of your refrigerator, set to high humidity. You may want to keep greens closer to the front to avoid frozen lettuce, Moyer suggests. Don’t wash your pre ...
Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]