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The first step in drug discovery is often measurement of the MICs of biological extracts, isolated compounds or large chemical libraries against bacteria and fungi of interest. [9] [10] MIC values provide a quantitative measure of an extract or compound's antimicrobial potency. The lower the MIC, the more potent the antimicrobial. [4]
Parts-per notation is often used describing dilute solutions in chemistry, for instance, the relative abundance of dissolved minerals or pollutants in water.The quantity "1 ppm" can be used for a mass fraction if a water-borne pollutant is present at one-millionth of a gram per gram of sample solution.
The ISMP recommends the non-SI symbol mcg instead. [1] However, the abbreviation mcg is also the symbol for an obsolete centimetre–gram–second system of units unit of measure known as millicentigram, which is equal to 10 μg. Gamma (symbol: γ) is a deprecated non-SI unit of mass equal to 1 μg. [2]
Half maximal inhibitory concentration (IC 50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological component by 50%. [1]
In chemistry, the most commonly used unit for molarity is the number of moles per liter, having the unit symbol mol/L or mol/dm 3 in SI units. A solution with a concentration of 1 mol/L is said to be 1 molar , commonly designated as 1 M or 1 M .
Usually, clearance is measured in L/h or mL/min. [2] Excretion, on the other hand, is a measurement of the amount of a substance removed from the body per unit time (e.g., mg/min, μg/min, etc.). While clearance and excretion of a substance are related, they are not the same thing.
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There are three common types of chemical reaction where normality is used as a measure of reactive species in solution: In acid-base chemistry, normality is used to express the concentration of hydronium ions (H 3 O +) or hydroxide ions (OH −) in a solution. Here, 1 / f eq is an integer value. Each solute can produce one or more ...