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Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. In addition to its use as a source of vitamin C, it is also used as an antioxidant food additive (E number E304). It is approved for use as a food additive in the EU, [1] the U.S., [2] Canada, [3] Australia, and New Zealand. [4]
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The water-soluble vitamin C derivatives such as ascorbic acid 2-glucoside and APPS (trisodium ascorbyl palmitate) can not add to water-soluble polymer gels commonly used in cosmetics such as carboxy vinyl polymer and sodium polyacrylate. This is because the viscosity changes, causing precipitation.
There is some information on serum vitamin C concentrations maintained in animal species that are able to synthesize vitamin C. One study of several breeds of dogs reported an average of 35.9 μmol/L. [ 70 ] A report on goats, sheep and cattle reported ranges of 100–110, 265–270 and 160–350 μmol/L, respectively.
An example of a mineral ascorbate drug is sodium ascorbate injections (the acid form, ascorbic acid, of vitamin c is too acidic for injections). Ascorbate salts may be better tolerated by the human body than the corresponding weakly acidic ascorbic acid. Ascorbates are highly reactive antioxidants used as food preservatives. [2]
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