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The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Title Skin (Layers, Glands, Vessels) Description The layers of skin (epidermis, dermis, and fatty tissue) and associated glands and vessels (blood vessels, follicle, oil gland, sweat gland, and melanocytes). Topics/Categories Anatomy -- Skin Type B&W, Medical Illustration Source National Cancer Institute
Cutis, often termed the "true skin", is composed of the epidermis and the dermis. [1] The dermis contains blood vessels, sweat glands, sebaceous glands, and hair follicles. [2] The epidermis and the dermis contain sensory nerve endings to detect changes in the environment. [2] The cutis is the layer located above the subcutis. [2
The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as from the stratum basale of the epidermis. The dermis is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region , and a deep thicker area known as the reticular region .
The basal layer is a stem cell layer and through asymmetrical divisions, becomes the source of skin cells throughout life. It is maintained as a stem cell layer through an autocrine signal, TGF alpha, and through paracrine signaling from FGF7 (keratinocyte growth factor) produced by the dermis below the
The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [8] [11] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound ...
A glomus body (or glomus organ; plural glomera) is a component of the dermis layer of the skin, involved in body temperature regulation. [1] [2] The glomus body is a small arteriovenous anastomosis surrounded by a capsule of connective tissue. Glomera are most numerous in the fingers and toes.
The reticular layer is the deep layer of the dermis and consists of the dense irregular connective tissue. These layers serve to give elasticity to the integument, allowing stretching and conferring flexibility, while also resisting distortions, wrinkling, and sagging. [3] The dermal layer provides a site for the endings of blood vessels and ...