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Chlorpromazine is in the typical antipsychotic class, [6] and, chemically, is one of the phenothiazines. Its mechanism of action is not entirely clear but is believed to be related to its ability as a dopamine antagonist. [6] It has antiserotonergic and antihistaminergic properties.
Typical antipsychotic. Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
Lunesta (eszopiclone) – a non-benzodiazepine hypnotic. Luvox (fluvoxamine) – an antidepressant of the SSRI class. Loxitane (loxapine) – an antipsychotic used in the treatment of mood disorders and schizophrenia. Lyrica (pregabalin) – treats nerve and muscle pain, including fibromyalgia. It can also treat seizures.
The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, and tardive akathisia.
Antipsychotics by class Generic name Brand names Chemical class ATC code ... Largactil, Thorazine: phenothiazine: N05AA01 Chlorprothixene: Cloxan, Taractan, Truxal:
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Clozapine is a dibenzodiazepine [38][39] that is structurally very similar to loxapine (originally deemed a typical antipsychotic). It is slightly soluble in water, soluble in acetone, and highly soluble in chloroform. Its solubility in water is 0.1889 mg/L (25 °C). [5]
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants. TCAs were discovered in the early 1950s and were marketed later in the decade. [1] They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms, are ...