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In a recent analysis (Susac et al., 2003), MRI images from 27 patients fulfilling the diagnostic criteria of Susac's syndrome were reviewed. Multifocal supratentorial lesions were present in all patients. Most lesions were small (3 to 7 mm), though some were larger than 7 mm. All 27 patients had corpus callosum lesions. These all had a punched ...
They occur most often as solitary, infratentorial lesions in young children. [3] In contrast, lesions are most often supratentorial in adults. [3] Pulmonary tuberculomas are among the most common benign nodules, with 5%-24% of all resected nodules being of tuberculous origin. [21]
Head CT showing periventricular white matter lesions. Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults. [1] [2] On MRI, leukoaraiosis changes appear as white matter hyperintensities (WMHs) in T2 FLAIR images.
Adults, on the other hand, don't show such propensity. [2] As a consequence, 37.7% of children affected by the tumor live to 4 years. [2] The effect of treatment strategies such as chemotherapy and radiation therapy on the prognosis of the disease is still controversial, with studies claiming either their benefits or their ineffectiveness. [2]
With a median age upon diagnosis of 3.5 years, this lesion is often a disease of infancy. They often reside supratentorial in the lateral ventricles of infants (most commonly in the atrium). [4] The fourth ventricle in adults is the optimum location. [5] Adults rarely have it at the cerebellopontine angle. [4]
Symptoms related to increased pressure in the brain often disappear after surgical removal of the tumor. Effects like seizures might progressively improve as recovery progresses. Steroid treatment is often used to control tissue swelling that may occur before and after surgery.
Astroblastoma is a rare glial tumor derived from the astroblast, a type of cell that closely resembles spongioblastoma and astrocytes. [1] Astroblastoma cells are most likely found in the supratentorial region of the brain that houses the cerebrum, an area responsible for all voluntary movements in the body. [2]
The supratentorial region contains the cerebrum, while the infratentorial region contains the cerebellum. Although the Roman era anatomist Galen commented upon it, the functional significance of this neuroanatomical division was first described using ‘modern’ terminology by John Hughlings Jackson , founding editor of the medical journal Brain .