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  2. IC50 - Wikipedia

    en.wikipedia.org/wiki/IC50

    Half maximal inhibitory concentration (IC 50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro , a given biological process or biological component by 50% ...

  3. Antibiotic sensitivity testing - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_sensitivity_testing

    A plastic strip impregnated with different concentrations of antibiotics is placed on a growth medium, and the growth medium is viewed after a period of incubation. [5] The minimum inhibitory concentration can be identified based on the intersection of the teardrop-shaped zone of inhibition with the marking on the strip. [5]

  4. Disk diffusion test - Wikipedia

    en.wikipedia.org/wiki/Disk_diffusion_test

    This is the zone of inhibition. In general, larger zones of inhibition correlate with lower minimum inhibitory concentrations (MICs) of antibiotic or extract for that bacterial strain. [1] An exception to this is when molecules of the antibiotic or extract are large or hydrophobic because these diffuse through the agar slowly. [6]

  5. European Committee on Antimicrobial Susceptibility Testing

    en.wikipedia.org/wiki/European_Committee_on...

    Like the Clinical and Laboratory Standards Institute, EUCAST offers guidelines to interpret raw minimum inhibitory concentrations (MICs), the lowest concentration of a chemical, usually a drug, which prevents visible growth of bacterium.

  6. Agar dilution - Wikipedia

    en.wikipedia.org/wiki/Agar_dilution

    Agar dilution is one of two methods (along with broth dilution) used by researchers to determine the minimum inhibitory concentration (MIC) of antibiotics. It is the dilution method most frequently used to test the effectiveness of new antibiotics when a few antibiotics are tested against a large panel of different bacteria. [1]: 149 [2]

  7. Minimum bactericidal concentration - Wikipedia

    en.wikipedia.org/wiki/Minimum_bactericidal...

    The minimum bactericidal concentration (MBC) is the lowest concentration of an antibacterial agent required to kill a particular bacterium. [1] It can be determined from broth dilution minimum inhibitory concentration (MIC) tests by subculturing to agar plates that do not contain the test agent.

  8. Broth microdilution - Wikipedia

    en.wikipedia.org/wiki/Broth_microdilution

    Varying concentrations of the antibiotics and the bacteria to be tested are then added to the plate. The plate is then placed into a non-CO 2 incubator and incubated at thirty-seven degrees Celsius for sixteen to twenty hours. Following the allotted time, the plate is removed and checked for bacterial growth.

  9. Minimum inhibitory concentration - Wikipedia

    en.wikipedia.org/wiki/Minimum_inhibitory...

    In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of a chemical, usually a drug, which prevents visible in vitro growth of bacteria or fungi. [ 1 ] [ 2 ] MIC testing is performed in both diagnostic [ 1 ] [ 2 ] and drug discovery laboratories.