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As in other mammals, human thermoregulation is an important aspect of homeostasis. In thermoregulation, body heat is generated mostly in the deep organs, especially the liver, brain, and heart, and in contraction of skeletal muscles. [1] Humans have been able to adapt to a great diversity of climates, including hot humid and hot arid.
The human body always works to remain in homeostasis. One form of homeostasis is thermoregulation. Body temperature varies in every individual, but the average internal temperature is 37.0 °C (98.6 °F). [1] Sufficient stress from extreme external temperature may cause injury or death if it exceeds the ability of the body to thermoregulate.
[1] Key to maintaining homeostasis, individual thermoregulation is the ability to maintain internal body temperature in humans, the most recognizable eurytherm. In humans, deep-body temperature is regulated by cutaneous blood flow, which maintains this temperature despite changes in the external environment. [24]
The cannabinoid receptor type 1, located at the presynaptic neuron, is a receptor that can stop stressful neurotransmitter release to the postsynaptic neuron; it is activated by endocannabinoids such as anandamide (N-arachidonoylethanolamide) and 2-arachidonoylglycerol via a retrograde signaling process in which these compounds are synthesized ...
As in other mammals, thermoregulation is an important aspect of human homeostasis. Most body heat is generated in the deep organs, especially the liver, brain, and heart, and in contraction of skeletal muscles. [15] Humans have been able to adapt to a great diversity of climates, including hot humid and hot arid.
[1] [2] For living organisms, it is life's foundational trait, consisting of a hierarchy and network of traits endowed by nature and shaped by natural selection. Homeostatic capacity comprises a multidimensional network of traits and operates at all scales of biology systems levels including molecular, cellular, physiological, and organismal.
The human outer or peripheral shell (skin, subcutaneous fat etc.) acts as an adjustable insulator/radiator with the main mechanism of adjustment being blood flow to this compartment. If the surroundings are warm then heat loss is less, so the body directs more blood to the periphery to maintain the gradient for energy flow.
Energy intake is measured by the amount of calories consumed from food and fluids. [1] Energy intake is modulated by hunger, which is primarily regulated by the hypothalamus, [1] and choice, which is determined by the sets of brain structures that are responsible for stimulus control (i.e., operant conditioning and classical conditioning) and cognitive control of eating behavior.