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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass dewormings; Drugs not members of these three main categories include: Diethylcarbamazine – effective against Wuchereria bancrofti, Brugia malayi, Brugia timori ...
Praziquantel is well absorbed (about 80%) from the gastrointestinal tract. However, due to extensive first-pass metabolism, only a relatively small amount enters systemic circulation. Praziquantel has a serum half-life of 0.8 to 1.5 hours in adults with normal renal and liver function. Metabolites have a half-life of 4 to 5 hours.
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
Oxamniquine acts mainly on male worms, but also induces small changes on a small proportion of females. Like praziquantel, it promotes more severe damage of the dorsal tegument than of the ventral surface. The drug causes the male worms to shift from the mesenteric circulation to the liver, where the cellular host response causes its final ...
Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. [1] It is taken by mouth. [2] Side effects may include abdominal pain, vomiting, headache, and dizziness. [2] Use is not recommended during breastfeeding or the third trimester ...
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