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According to clinical studies performed prior to marketing: The oral toxicity profile of afoxolaner consists of a diuretic effect (rats only), effects secondary to a reduction in food consumption (rats and rabbits only) and occasional vomiting and/or diarrhea (dogs, 120 and 200 mg/kg bodyweight (bw)) following high oral doses.
A mycotoxin is suspected to be involved, but none has been found in grapes or raisins ingested by affected dogs. [5] The dose-response relationship has not been determined, [2] but one study estimated 3 g/kg or greater for grapes or raisins. [6] An April 2021 letter to the editor of JAVMA hypothesized that the tartaric acid in grapes could be ...
There are approximately 86.4 million pet cats and approximately 78.2 million pet dogs in the United States, [9] [10] and a United States 2007–2008 survey showed that dog-owning households outnumbered those owning cats, but that the total number of pet cats was higher than that of dogs.
Details of structures vary tremendously from breed to breed, more than in any other animal species, wild or domesticated, [1] as dogs are highly variable in height and weight. The smallest known adult dog was a Yorkshire Terrier that stood only 6.3 cm (2.5 in) at the shoulder, 9.5 cm (3.7 in) in length along the head and body, and weighed only ...
In the British standard a weight of 1.8–2.7 kg (4–6 lb) is preferred – the clause "if two dogs are equally good in type, the more diminutive one is preferred" was removed in 2009. [ 15 ] Pet Chihuahuas (those bred or purchased as companions rather than as show dogs) often range above these weights, even above 4.5 kg (10 lb), if they have ...
The Original Dog Bible: The Definitive Source for All Things Dog. Irvine, CA: Bow Tie Press. ISBN 1-931993-34-3. Morris, Desmond (2001). Dogs: The Ultimate Dictionary of over 1,000 Dog Breeds. North Pomfret, VT: Trafalgar Square Publishing. ISBN 1-57076-219-8. Soman, W.V. (1962). The Indian Dog. Mumbai: Popular Prakashan.
The African wild dog (Lycaon pictus), also called painted dog and Cape hunting dog, is a wild canine native to sub-Saharan Africa.It is the largest wild canine in Africa, and the only extant member of the genus Lycaon, which is distinguished from Canis by dentition highly specialised for a hypercarnivorous diet and by a lack of dewclaws.
The Cessna O-1 Bird Dog is a liaison and observation aircraft that first flew on December 14, 1949, and entered service in 1950 as the L-19 in the Korean War. It went to serve in many branches of the U.S. Armed Forces, was not retired until the 1970s in a number of variants, and also served in the Vietnam War .