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Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group. [5] It is prescribed for nausea and vomiting due to motion sickness [6] or other sources such as chemotherapy, [7] vertigo, [8] or Ménière's disease. [9] Cinnarizine is one of the leading causes of drug-induced parkinsonism. [5]
"Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866– 77.
As the article states, cinnarizine is a CNS depressant, that is, it has antihistaminic, antiserotonergic, antidopaminergic effects. How strong, you ask? Strong enough not to be approved. One example: the usual dosage is supposed to be 2-3 tablets a day. Here I will describe effects on a test subject at a dose of 2 tablets a day.
2 1/2 oz. Fill a cocktail mixing glass or medium glass measuring cup with ice. Add gin, vermouth, and olive brine. Vigorously stir until very cold, 30 to 45 seconds. Strain into a chilled martini ...
[52] [53] In rats, less than 2% of the drug is excreted unchanged. [53] The time to reach maximum concentration (T max) of hydroxyzine is about 2.0 hours in both adults and children and its elimination half-life is around 20.0 hours in adults (mean age 29.3 years) and 7.1 hours in children.
A sicko from New Jersey allegedly took part in a neo-Nazi child-porn ring whose members groomed children online and extorted them to send self-produced, sexually-explicit videos, federal ...
Image credits: father_of_twitch #2. Slow down to speed up. 'Slow is accurate, and accurate is fast'. Rushing through everything causes stress, anxiety, mistakes, and costs money.
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]