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  2. Blood substitute - Wikipedia

    en.wikipedia.org/wiki/Blood_substitute

    A blood substitute (also called artificial blood or blood surrogate) is a substance used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion , which is transferring blood or blood-based products from one person into another.

  3. Autoimmune regulator - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_regulator

    The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. [5] It is a 13kbp gene on chromosome 21q22.3 that encodes 545 amino acids. [6] AIRE is a transcription factor expressed in the medulla [broken anchor] (inner part) of the thymus.

  4. Antibody–drug conjugate - Wikipedia

    en.wikipedia.org/wiki/Antibody–drug_conjugate

    In 2001 Pfizer/Wyeth's drug Gemtuzumab ozogamicin (trade name: Mylotarg) was approved based on a study with a surrogate endpoint, through the accelerated approval process. In June 2010, after evidence accumulated showing no evidence of benefit and significant toxicity, the U.S. Food and Drug Administration (FDA) forced the company to withdraw ...

  5. Thiamine pyrophosphate - Wikipedia

    en.wikipedia.org/wiki/Thiamine_pyrophosphate

    To date, the yeast ThPP carrier (Tpc1p) the human Tpc and the Drosophila melanogaster have been identified as being responsible for the mitochondrial transport of ThPP and ThMP. [ 2 ] [ 3 ] [ 4 ] It was first discovered as an essential nutrient ( vitamin ) in humans through its link with the peripheral nervous system disease beriberi , which ...

  6. Fuel surrogate - Wikipedia

    en.wikipedia.org/wiki/Fuel_surrogate

    [citation needed] Jet fuel is an example of a fuel requiring a surrogate for experimental research and numerical modelling due to its complexity and high content variability from one batch to the next. [1] [non-primary source needed] Neat hydrocarbon jet fuel surrogate components include decane, dodecane, methylcyclohexane, and toluene.

  7. Quizlet - Wikipedia

    en.wikipedia.org/wiki/Quizlet

    Quizlet was founded in 2005 by Andrew Sutherland as a studying tool to aid in memorization for his French class, which he claimed to have "aced". [6] [7] [8] ...

  8. Monocarboxylate transporter - Wikipedia

    en.wikipedia.org/wiki/Monocarboxylate_transporter

    There are 14 MCTs corresponding to 14 solute carrier 16A transporters, although the cardinal numbers do not match (for example MCT3 is SLC16A8). [2] MCTs 1-4 have been more carefully investigated than MCTs 5-14. [2] MCTs can be upregulated by PPAR-α, HIF-1α, Nrf2, and AMPK. [2]

  9. Charge transport mechanisms - Wikipedia

    en.wikipedia.org/wiki/Charge_transport_mechanisms

    Carrier mobility strongly depends on the concentration of localized states in a non-linear fashion. [2] In the case of nearest-neighbour hopping , which is the limit of low concentrations, the following expression can be fitted to the experimental results: [ 3 ]

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