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Louis Pasteur - pioneering stereochemist. Chirality can be traced back to 1812, when physicist Jean-Baptiste Biot found out about a phenomenon called "optical activity." [10] Louis Pasteur, a famous student of Biot's, made a series of observations that led him to suggest that the optical activity of some substances is caused by their molecular asymmetry, which makes nonsuperimposable mirror ...
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This term has become very popular and commonly used in practice. But the appropriate expression is "enantioselective chromatography". [34] Chiral chromatography has advanced to turn into the most preferred technique for the determination of enantiomeric purity as well as separation of pure enantiomers both on analytical and preparative scale.
An enantiopure drug is a pharmaceutical that is available in one specific enantiomeric form. Most biological molecules (proteins, sugars, etc.) are present in only one of many chiral forms, so different enantiomers of a chiral drug molecule bind differently (or not at all) to target receptors. Chirality can be observed when the geometric ...
East African drug trade refers to the sale and trafficking of illegal drugs that take place in East African countries like Kenya, Tanzania, Uganda, Somalia, and Ethiopia. . The most prevalent types of drugs traded in East Africa are heroin, marijuana, cocaine, methamphetamine, and khat, all of which are strictly prohibited in East African countri
Many young people in West and Central Africa have become addicted to drugs with between 5.2% and 13.5% using cannabis, the most widely used illicit substance on the continent, according to the ...
Fenoprofen is chiral drug with one stereogenic center and exists as chiral twins. (S)-enantiomer has the desired pharmacological action where as the (R)-isomer is less active. It is observed that there is stereoselective bioconversion of the (R)- to (S)-fenoprofen. This stereoselective conversion is called chiral inversion. [5] [6]
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