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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Houston is experiencing an outbreak of syphilis, the city’s health department recently revealed.Cases of the sexually transmitted infection jumped a jaw-dropping 128% in women from 2019 to 2022 ...
A chancre (/ ˈ ʃ æ ŋ k ər / SHANG-kər) [1] is a painless genital ulcer most commonly formed during the primary stage of syphilis. [2] This infectious lesion forms around 21 days after the initial exposure to Treponema pallidum, the gram-negative spirochaete bacterium causing syphilis, but can range from 10 to 90 days. [2]
Another example is tertiary syphilis, where changes to teeth can occur. [2] Syphilis infection can be associated with longitudinal furrows of the tongue. Mineral and vitamin deficiencies can cause the tongue to appear beefy red and feel sore. Those deficiencies are iron, folate, and vitamin B12.
Additionally, syphilis can cause painless red sores on the penis, called chancres. Finally, human papillomavirus (HPV), can cause genital warts and Bowenoid papulosis.”
Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
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Both Jarisch and Herxheimer observed reactions in patients with syphilis treated with mercury. The reaction was first seen following treatment in early and later stages of syphilis treated with Salvarsan, mercury, or antibiotics. Jarisch thought that the reaction was caused by a toxin released from the dying spirochetes. [11]
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