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The discovery in 1953 of the double helix, the twisted-ladder structure of deoxyribonucleic acid (DNA), by James Watson and Francis Crick marked a milestone in the history of science and gave rise to modern molecular biology, which is largely concerned with understanding how genes control the chemical processes within cells.
Rosalind Franklin in a letter to Ellis Franklin, ca. summer 1940. Rosalind Elsie Franklin, the brilliant chemist whose x-ray diffraction studies provided crucial clues to the structure of DNA and quantitatively confirmed the Watson-Crick DNA model, was born in London on July 25, 1920, the second of five children in a prominent Anglo-Jewish family.
About this Collection. The name of British Nobel laureate Francis Crick (1916-2004) is inextricably tied to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in the understanding of biology since Darwin's theory of evolution. Yet, during a research career spanning more than fifty ...
In 1953, James Watson and Francis Crick determined the double helix structure of DNA. Thus, Avery played an early and critical role in the molecular revolution in biology. Soon after starting at the Rockefeller Institute, Avery began to share an apartment with Dochez, who was then a colleague in the respiratory disease department at the Hospital.
The name of British Nobel laureate Francis Crick (1916-2004) is inextricably tied to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in the understanding of biology since Darwin's theory of evolution. ... (1920-1958) was a British chemist and crystallographer who is best known ...
The Discovery of the Double Helix, 1951-1953; Defining the Genetic Coding Problem, 1954-1957; Deciphering the Genetic Code, 1958-1966; Embryology and the Organization of DNA in Higher Organisms, 1966-1976; From Molecular Biology to Neurobiology, 1976-2004; Additional Resources; Glossary; Collection Items
The two linked strands are twisted in a double helix. Double helix -- A helix or spiral consisting of two strands in the surface of a cylinder that coil around its axis; especially the structural arrangement of DNA in space that consists of paired polynucleotide strands stabilized by cross-links between purine and pyrimidine bases.
The Discovery of the Double Helix, 1951-1953; Defining the Genetic Coding Problem, 1954-1957; Deciphering the Genetic Code, 1958-1966; Embryology and the Organization of DNA in Higher Organisms, 1966-1976; From Molecular Biology to Neurobiology, 1976-2004; Additional Resources; Glossary; Collection Items
12. The Double Helix Revisited--Francis Crick and James Watson Talk to Paul Vaughan about Their Discovery of the Molecular Structure of DNA. 13. Letter from Francis Crick to James D. Watson. 14. Letter from Linus Pauling to Francis Crick. 15. Letter from James D. Watson to Francis Crick.
Glossary. Alpha-helix -- A short, helical arrangement of a polypeptide chain that is a common secondary structure in proteins. In the alpha-helix, the polypeptide folds by twisting into a right handed screw so that all the amino acids can form hydrogen bonds with each other. Base pair -- Either of the two pairs--guanine and cytosine, adenine ...