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Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [1][2] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells.
Tricyclic antidepressant overdose is poisoning caused by excessive medication of the tricyclic antidepressant (TCA) type. Symptoms may include elevated body temperature, blurred vision, dilated pupils, sleepiness, confusion, seizures, rapid heart rate, and cardiac arrest. [ 1 ] If symptoms have not occurred within six hours of exposure they are ...
Benzodiazepines, cyproheptadine [ 1 ] Frequency. Unknown [ 3 ] Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [ 1 ] The symptoms can range from mild to severe, and are potentially fatal. [ 4 ][ 5 ][ 2 ] Symptoms in mild cases include high blood pressure and a fast heart ...
Nortriptyline is a less preferred treatment for ADHD and stopping smoking. [ 6 ] It is taken by mouth. [ 6 ] Common side effects include dry mouth, constipation, blurry vision, sleepiness, low blood pressure with standing, and weakness. [ 6 ] Serious side effects may include seizures, an increased risk of suicide in those less than 25 years of ...
Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [ 11 ] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [ 92 ]
Atropine/diphenoxylate. Diphenoxylate/atropine, also known as co-phenotrope, is a combination of the medications diphenoxylate and atropine, used to treat diarrhea. [ 2 ][ 3 ] It should not be used in those in whom Clostridioides difficile infection is a concern. [ 4 ] It is taken by mouth. [ 2 ]
A muscarinic receptor antagonist (MRA), also called an antimuscarinic, is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor. The muscarinic receptor is a protein involved in the transmission of signals through certain parts of the nervous system, and muscarinic receptor antagonists work to prevent ...
Toxidrome [1] A toxidrome (a portmanteau of toxic and syndrome, coined in 1970 by Mofenson and Greensher [2]) is a syndrome caused by a dangerous level of toxins in the body. It is often the consequence of a drug overdose. Common symptoms include dizziness, disorientation, nausea, vomiting and oscillopsia. It may indicate a medical emergency ...