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Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [3][4] Evidence supports slight to moderate benefit up to six months. [5][4][6] It is taken by mouth. [3][5] Common side effects include headache, dry mouth, nausea, and dizziness. [5] Severe side effects may include suicidal thoughts ...
Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7][4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Zolpidem is a nonbenzodiazepine, or Z-drug, which acts as a sedative and hypnotic. [11][20] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [11] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [11]
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
Daridorexant. Daridorexant, sold under the brand name Quviviq, is an orexin antagonist medication which is used for the treatment of insomnia. [ 1 ][ 4 ][ 6 ][ 7 ][ 8 ] Daridorexant is taken by mouth. [ 1 ][ 4 ][ 7 ] Side effects of daridorexant include headache, somnolence, and fatigue. [ 1 ][ 7 ] The medication is a dual orexin receptor ...
Zopiclone is a sedative. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result.
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