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Depression is a mental state of low mood and aversion to activity. [ 3] It affects more than 280 million people of all ages (about 3.5% of the global population). [ 4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [ 5] Depressed people often experience loss of motivation or interest in, or reduced pleasure ...
Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [ 8] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 9] the term was adopted by the American ...
A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
"Regular exercise can increase self-confidence, improve your mood, help you relax, and lower symptoms of mild depression and anxiety," states Mayo Clinic. Clear your mind with meditation
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
In the mid-20th century, researchers theorized that depression was caused by a chemical imbalance in neurotransmitters in the brain, a theory based on observations made in the 1950s of the effects of reserpine and isoniazid in altering monoamine neurotransmitter levels and affecting depressive symptoms. [ 32]
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