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Depression is a mental state of low mood and aversion to activity. [ 3] It affects more than 280 million people of all ages (about 3.5% of the global population). [ 4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [ 5] Depressed people often experience loss of motivation or interest in, or reduced pleasure ...
Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [ 8] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 9] the term was adopted by the American ...
Medication. Antidepressants, mood stabilizers, antipsychotics [ 1] A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder [ 2] where a disturbance in the person's mood is the main underlying feature. [ 3] The classification is in the Diagnostic and Statistical Manual of Mental ...
A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
Beck's cognitive triad. A diagram showing Beck's cognitive triad. Beck's cognitive triad, also known as the negative triad, [ 1][ 2] is a cognitive-therapeutic view of the three key elements of a person's belief system present in depression. It was proposed by Aaron Beck in 1967. [ 3]
The DSM-IV defines depressive personality disorder as "a pervasive pattern of depressive cognitions and behaviors beginning by early adulthood and occurring in a variety of contexts." Depressive personality disorder occurs independently of major depressive episodes, making it a distinct diagnosis not included in the definition of either major ...
In the mid-20th century, researchers theorized that depression was caused by a chemical imbalance in neurotransmitters in the brain, a theory based on observations made in the 1950s of the effects of reserpine and isoniazid in altering monoamine neurotransmitter levels and affecting depressive symptoms. [ 32]
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
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