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Tumors of the hematopoietic and lymphoid tissues ( American English) or tumours of the haematopoietic and lymphoid tissues ( British English) are tumors that affect the blood, bone marrow, lymph, and lymphatic system. [1] [2] Because these tissues are all intimately connected through both the circulatory system and the immune system, a disease ...
Lymphoma is the most common form of hematological malignancy, or "blood cancer", in the developed world. Taken together, lymphomas represent 5.3% of all cancers (excluding simple basal cell and squamous cell skin cancers) in the United States and 55.6% of all blood cancers.
Hodgkin lymphoma ( HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes. [ 2][ 8] The condition was named after the English physician Thomas Hodgkin, who first described it in 1832. [ 9 ...
111,000 (2015) [ 10] Acute lymphoblastic leukemia ( ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [ 1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [ 1]
Lymphokine-activated killer cell. In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell, consisting mostly of natural killer, natural killer T, and T cells that has been stimulated to kill tumor cells, but because of the function in which they activate, and the cells they can successfully target ...
In the case of a bone-marrow transplant, the HSCs are removed from a large bone of the donor, typically the pelvis, through a large needle that reaches the center of the bone. The technique is referred to as a bone-marrow harvest and is performed under local or general anesthesia.
Graft-versus-leukemia. Graft-versus-leukemia (GvL) is a specific type of GvT effect. As the name of this effect indicates, GvL is a reaction against leukemic cells of the host. GvL requires genetic disparity because the effect is dependent on the alloimmunity principle. GvL is a part of the reaction of the graft against the host.
Marked male predominance [ 1] T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia characterized by an aggressive malignant neoplasm of the bone marrow. [ 6] Acute lymphoblastic leukemia (ALL) is a condition where immature white blood cells accumulate in the bone marrow, subsequently crowding out normal white ...