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Tumors of the hematopoietic and lymphoid tissues ( American English) or tumours of the haematopoietic and lymphoid tissues ( British English) are tumors that affect the blood, bone marrow, lymph, and lymphatic system. [1] [2] Because these tissues are all intimately connected through both the circulatory system and the immune system, a disease ...
122–184. Lymphoma is the most common form of hematological malignancy, or "blood cancer", in the developed world. Taken together, lymphomas represent 5.3% of all cancers (excluding simple basal cell and squamous cell skin cancers) in the United States and 55.6% of all blood cancers.
Chronic lymphocytic leukemia. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur ...
Hodgkin lymphoma ( HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes. [ 2][ 8] The condition was named after the English physician Thomas Hodgkin, who first described it in 1832. [ 9 ...
In the case of a bone-marrow transplant, the HSCs are removed from a large bone of the donor, typically the pelvis, through a large needle that reaches the center of the bone. The technique is referred to as a bone-marrow harvest and is performed under local or general anesthesia.
Lymphoid cells include T cells, B cells, natural killer cells, and innate lymphoid cells. The definition of hematopoietic stem cell has developed since they were first discovered in 1961. [5] The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent ...
T-cell lymphoma. Micrograph of an enteropathy-associated T-cell lymphoma (upper right of image), a type of T-cell lymphoma. H&E stain. T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. [ 1] Lymphoma arises mainly from the uncontrolled proliferation of T-cells and can become cancerous. [ 2]
Variant form of nodular lymphocyte predominant Hodgkin lymphoma. T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a malignancy of B cells. B-cells are lymphocytes that normally function in the humoral immunity component of the adaptive immune system by secreting antibodies that, for example, bind to and neutralize invasive pathogens ...