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Occasionally symptoms can last up to one year. [3] They typically resolve within a day of restoring the medication. [20] Paroxetine and venlafaxine seem to be particularly difficult to discontinue, and prolonged withdrawal syndrome (post-acute-withdrawal syndrome, or PAWS) lasting over 18 months has been reported with paroxetine. [21] [22] [23]
As noted above, many drugs should not be stopped abruptly [10] without the advice and supervision of a physician, especially if the medication induces dependence or if the condition they are being used to treat is potentially dangerous and likely to return once medication is stopped, such as diabetes, asthma, heart conditions and many ...
Hypomania, [7] [unreliable medical source] [8] [9] [unreliable medical source] may occur in as many as 8% of patients being treated with paroxetine. May be more common in those with bipolar disorder. Asthenia; Weight gain or loss. Usually gain, paroxetine tends to produce more weight gain than other SSRIs. [6]: 58 Confusion; Emotional lability ...
Another example of pharmaceutical rebound is a rebound headache from painkillers when the dose is lowered, the medication wears off, or the drug is abruptly discontinued. [ 18 ] In 2022, reports of viral RNA and symptom rebound in people with COVID-19 treated with Paxlovid were published.
According to a 2008 study, taking an SSRI with a benzodiazepine can help regulate anxiety quickly. It can also help patients deal with the agitation that can occur when you first start taking an SSRI.
Paroxetine was the first antidepressant approved in the United States for the treatment of panic disorder. [27] [page needed] Several studies have concluded that paroxetine is superior to placebo in the treatment of panic disorder. [25] [28] Paroxetine has demonstrated efficacy for the treatment of social anxiety disorder in adults and children.
“I don’t want to interrupt your week…” Whiteside began to explain. Mary’s reply was quick and firm. “No, no, no, no, no, no. Don’t stop,” she told her. “Don’t stop.” Over time, Mary has built up a support system and finally feels comfortable enough to go to softball games with friends or on trips to see her family.
[4] [5] Physical dependence can develop from low-dose therapeutic use of certain medications such as benzodiazepines, opioids, stimulants, antiepileptics and antidepressants, as well as the recreational misuse of drugs such as alcohol, opioids and benzodiazepines. The higher the dose used, the greater the duration of use, and the earlier age ...