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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
N-Phenylglycine is an organic compound with the formula C 6 H 5 NHCH 2 CO 2 H. This white solid achieved fame as the industrial precursor to indigo dye . [ 1 ] It is a non-proteinogenic alpha amino acid related to sarcosine , but with an N - phenyl group in place of N - methyl .
Print/export Download as PDF; Printable version; In other projects ... Synonyms CAS number CaAl 2 O 4: calcium aluminate: 12042-68-1 CaB 6: calcium boride:
Biosynthesis of HPG. HPG is synthesized from prephenate, an intermediate in the shikimic acid pathway and also a precursor to tyrosine.Prephenate is aromatized by prephenate dehydrogenase (Pdh) using NAD + as a cofactor to produce 4-hydroxyphenylpyruvate. 4-Hydroxyphenylpyruvate is then oxidized by 4-hydroxymandelate synthase (4HmaS) using oxygen to form 4-hydroxymandelate and hydrogen ...
Glycine methyl ester hydrochloride can be prepared by treatment of glycine with 2 equivalents of trimethylsilyl chloride, followed by the addition of methanol. [2] [3]Upon treatment with base, the salt converts to glycine methyl ester.
When synthesized in bacteria, DHPG requires 5 enzymes, DpgA-D and 4-hydroxyphenylglycine transferase (Pgat), in order to be synthesized. [4] DpgA is a type III polyketide synthase and initiates the synthesis by condensing acetyl-CoA with three molecules of malonyl-CoA.
(RS)-MCPG is a phenylglycine derivative and a non-selective antagonist of group I and II metabotropic glutamate receptors (mGluRs). It has been used in long-term potentiation (LTP) as well as long-term depression (LTD) research and proved that certain LTP and LTD pathways depend on mGluRs.
The ionic form of the DNPBG (3,5-dinitrobenzoyl-phenylglycine) CSP has been successfully employed to achieve separation of racemic propranolol in biological fluid. Many compounds of pharmaceutical interest including enantiomers of naproxen and metoprolol has been separated using Pirkle CSP.