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Mifepristone, and also known by its developmental code name RU-486, is a drug typically used in combination with misoprostol to bring about a medical abortion during pregnancy. [8] This combination is 97% effective [9] during the first 63 days (9 weeks) of pregnancy, yet effective in the second trimester as well.
Mifepristone is used in more than half of all abortions in the US. The drug was first approved for use by the US Food and Drug Administration in most cases up to 10 weeks of pregnancy in 2000.
Mifepristone is currently in the middle of a political tug-of-war, with some conservative states seeking to restrict or eliminate access to the abortion pill, while other states are trying to ...
But mifepristone has many uses in reproductive care and in other contexts, experts say. Mifepristone is one of two drugs used in medication abortion in the U.S. But mifepristone has many uses in ...
Emergency contraception pills ("morning after pills") are taken at the time of intercourse, or within a few days afterwards: Levonorgestrel, sold under the brand name Plan B; Ulipristal acetate; Mifepristone and misoprostol, when used in combination, are more than 95% effective during the first 50 days of pregnancy.
Aid Access is a nonprofit organization that provides access to medication abortion by mail to the United States and worldwide. It describes its work as a harm reduction strategy designed to provide safe access to mifepristone and misoprostol for those able to become pregnant in the United States who may not otherwise have access to abortion or miscarriage management services. [2]
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In 2000, GenBioPro's generic version of mifepristone was approved for medication abortion, as part of a two-drug regimen in combination with misoprostol. In 2023, GenBioPro sued the FDA to obtain a legal judgement confirming that mifepristone could continue to be sold, in spite of anti-abortion laws passed in some states.