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The sealant material consists of polyethylene glycol (PEG), a water-soluble, non-thrombogenic, conformable, bio-inert polymer. PEG has an established safety profile [ 2 ] and various forms of PEG are commonly used in a range of consumer and medical products including toothpaste , skin cream and lubricant eye drops .
In its uncured state, silicone rubber is a highly adhesive gel or liquid. To convert it to a solid, it must be cured, vulcanized, or catalyzed.This is normally carried out in a two-stage process at the point of manufacture into the desired shape, and then in a prolonged post-cure process.
Fibrin glue (also called fibrin sealant) is a surgical formulation used to create a fibrin clot for hemostasis, cartilage repair surgeries or wound healing. It contains separately packaged human fibrinogen and human thrombin .
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Sealant is a substance used to block the passage of fluids through openings in materials, [1] a type of mechanical seal. In building construction sealant is sometimes synonymous with caulk (especially if acrylic latex or polyurethane based) [ 2 ] and also serve the purposes of blocking dust, sound and heat transmission.
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Typically the sealant products manufactured with silyl-modified polymers have good adhesion on a wide range of substrate materials, and have good temperature and UV resistance. MS polymers consist of a polyether backbone with dimethoxy-silyl or trimethoxy-silyl ends, with trimethoxy-silyl groups being more reactive.