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  2. Heterophile antibody test - Wikipedia

    en.wikipedia.org/wiki/Heterophile_antibody_test

    The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection.

  3. Heterophile antibody - Wikipedia

    en.wikipedia.org/wiki/Heterophile_antibody

    Heterophile antibodies are IgM antibodies with affinity for sheep and horse red blood cells. They appear during the first week of infectious mononucleosis symptoms, 3–4 weeks after infection and return to undetectable levels 3 to 6 months after infection. Heterophile antibody is a fairly specific but insensitive test for EBV.

  4. Epstein–Barr virus–associated lymphoproliferative diseases

    en.wikipedia.org/wiki/Epstein–Barr_virus...

    Epstein–Barr virus–associated lymphoproliferative diseases (also abbreviated EBV-associated lymphoproliferative diseases or EBV+ LPD) are a group of disorders in which one or more types of lymphoid cells (a type of white blood cell), i.e. B cells, T cells, NK cells, and histiocytic-dendritic cells, are infected with the Epstein–Barr virus (EBV).

  5. Epstein–Barr virus infection - Wikipedia

    en.wikipedia.org/wiki/Epstein–Barr_virus_infection

    Blood test results for persons with infectious mononucleosis include an elevated white blood cell count, an increased percentage of atypical mononuclear cells. Liver enzymes are often elevated. A positive "mono spot" test is useful in confirming the diagnosis but a negative result does not rule out primary EBV infection.

  6. Chronic active EBV infection - Wikipedia

    en.wikipedia.org/wiki/Chronic_active_EBV_infection

    Chronic active EBV infection or in its expanded form, chronic active Epstein–Barr virus infection is a very rare and often fatal complication of Epstein–Barr virus (EBV) infection that most often occurs in children or adolescents of Asian or South American lineage, although cases in Hispanics, Europeans and Africans have been reported. [1]

  7. Infectious mononucleosis - Wikipedia

    en.wikipedia.org/wiki/Infectious_mononucleosis

    Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...

  8. Reactive lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Reactive_lymphocyte

    Reactive lymphocytes were originally described by W. Türk in 1907 in the peripheral blood of patients with infectious mononucleosis. Later in 1923 the features of the reactive lymphocytes were characterized in greater detail by Hal Downey and C.A. McKinlay, who also discovered the association with EBV and CMV. [1] [2]

  9. Epstein–Barr virus - Wikipedia

    en.wikipedia.org/wiki/Epstein–Barr_virus

    Epstein–Barr virus snoRNA1 is a box CD-snoRNA generated by the virus during latency. V-snoRNA1 may act as a miRNA-like precursor that is processed into 24 nucleotide sized RNA fragments that target the 3'UTR of viral DNA polymerase mRNA. [39] ebv-sisRNA: latent Ebv-sisRNA-1 is a stable intronic sequence RNA generated during latency program III.