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Cervicocranial syndrome or (craniocervical junction syndrome, CCJ syndrome) is a combination of symptoms that are caused by an abnormality in the cervical vertebrae leading to improper function of cervical spinal nerves. Cervicocranial syndrome is either congenital [1] or acquired. [2]
Craniocervical instability is more common in people with a connective tissue disease, including Ehlers-Danlos syndromes, [1] osteogenesis imperfecta, and rheumatoid arthritis. [2] It is frequently co-morbid with atlanto-axial joint instability, Chiari malformation , [ 3 ] or tethered spinal cord syndrome .
The cruciate ligament of the atlas consists of the transverse ligament of the atlas, a superior longitudinal band, and an inferior longitudinal band. [1] [2] The superior longitudinal band connects the transverse ligament to the anterior side of the foramen magnum (near the basilar part) in the occipital bone of the skull.
A study using upright MRI found cerebellar tonsillar ectopia in 23% of adults with headache from motor-vehicle-accident head trauma. Upright MRI was more than twice as sensitive as standard MRI, likely because gravity affects cerebellar position. [22] Cases of congenital Chiari malformation may be explained by evolutionary and genetic factors.
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Craniocervical junction misalignment is also suspected as a factor in neurodegenerative diseases where altered CSF flow plays a part in the pathological process. Hyperextension (Whiplash) Injury A rear-end traffic collision or a poorly performed rugby tackle can both result in the head being whipped back on the shoulders, causing whiplash.
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One study found that male German Shepherd Dogs with a lumbosacral transitional vertebra are at greater risk for cauda equina syndrome, which can cause rear limb weakness and incontinence. [ 10 ] The significance of transitional vertebrae has been questioned by one study finding similar prevalence in the general population as those with low back ...