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Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...
Folate in the form of folic acid is used to treat anemia caused by folate deficiency. [3] Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. [3] [10] NTDs include anencephaly and spina bifida, among other defects.
Megaloblastic anemia, the most common cause of macrocytic anemia, is due to a deficiency of either vitamin B 12, folic acid, or both. [81] Deficiency in folate or vitamin B 12 can be due either to inadequate intake or insufficient absorption. Folate deficiency normally does not produce neurological symptoms, while B 12 deficiency does.
Eyes can be itchy, watery, bloodshot and sensitive to light. Riboflavin deficiency also causes anemia with red blood cells that are normal in size and hemoglobin content, but reduced in number. This is distinct from anemia caused by deficiency of folic acid or vitamin B 12. [21] [22]
Micronutrient deficiency is defined as the sustained insufficient supply of vitamins and minerals needed for growth and development, as well as to maintain optimal health. Since some of these compounds are considered essentials (we need to obtain them from the diet), micronutrient deficiencies are often the result of an inadequate intake.
Desert vegetation in Wadi Rum, southern Jordan. The wildlife of Jordan includes its flora and fauna and their natural habitats. Although much of the country is desert, it has several geographic regions, each with a diversity of plants and animals adapted to their own particular habitats.
Human remains found in a desert in 1992 have now been identified as a missing 15-year-old girl, Arizona officials said. The “decomposed remains were found in a remote desert area” of Apache ...
Correction of the systemic folate deficiency, with the normalization of folate blood levels, is easily achieved with high doses of oral folates or much smaller doses of parenteral folate. [1] [6] [7] [8] This will rapidly correct the anemia, immune deficiency and GI signs. The challenge is to achieve adequate treatment of the neurological ...