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  2. Amyloid plaques - Wikipedia

    en.wikipedia.org/wiki/Amyloid_plaques

    The diagnosis of Alzheimer's disease typically requires a microscopic analysis of plaques and tangles in brain tissue, usually at autopsy. [40] However, Aβ plaques (along with cerebral Aβ-amyloid angiopathy ) can be detected in the brains of living subjects by preparing radiolabeled agents that bind selectively to Aβ deposits in the brain ...

  3. New study challenges amyloid-beta theory on cause for ... - AOL

    www.aol.com/study-challenges-amyloid-beta-theory...

    A main theory behind the cause of Alzheimer’s disease is the build-up of the protein amyloid-beta in the brain. Researchers from the University of Cincinnati provide evidence suggesting it’s ...

  4. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    The term senile dementia of the Alzheimer type (SDAT) was used for a time to describe the condition in those over 65, with classical Alzheimer's disease being used to describe those who were younger. Eventually, the term Alzheimer's disease was formally adopted in medical nomenclature to describe individuals of all ages with a characteristic ...

  5. Biomarkers of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_Alzheimer's...

    Aβ42 is the initial and major component of amyloid plaque deposits. While the most prevalent hypothesis for mechanisms of Aβ-mediated neurotoxicity is structural damage to the synapse, various mechanisms such as oxidative stress, [ 6 ] altered calcium homeostasis, induction of apoptosis , structural damage, chronic inflammation and neuronal ...

  6. Labcorp launches 3-part blood test for Alzheimer's - AOL

    www.aol.com/news/labcorp-launches-3-part-blood...

    Alzheimer's, which gradually destroys memory and thinking skills, is characterized by a slow build-up of proteins in the brain in the form of amyloid plaques and tau tangles that eventually cause ...

  7. Biochemistry of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Biochemistry_of_Alzheimer's...

    The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy : a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain . [ 1 ]

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