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The antimicrobial and antibiotic effects of macrolides, however, are not believed to be involved in their beneficial effects toward treating DPB. [13] This is evident, as the treatment dosage is much too low to fight infection, and in DPB cases with the occurrence of the macrolide-resistant bacterium Pseudomonas aeruginosa , macrolide therapy ...
Clindamycin may prolong the effects of neuromuscular-blocking drugs, such as succinylcholine and vecuronium. [55] [56] [57] Its similarity to the mechanism of action of macrolides and chloramphenicol means they should not be given simultaneously, as this causes antagonism [26] and possible cross-resistance. [medical citation needed]
Lincosamides can interact with anesthetic agents to produce neuromuscular effects. [29] Other adverse reactions include diarrhea, nausea, vomiting, abdominal pain and rash. Topical administration of clindamycin may induce contact dermatitis, dryness, burning, itching, scaliness and peeling of the skin. [30]
Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis. [3] A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality. [4] It was released for medical use in September 1964. [5]
Two separate patients who were prescribed a popular class of antibiotic told WFTS the drug ... there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million ...
The incidence of inner ear toxicity varies from 7 to 90%, depending on the types of antibiotics used, susceptibility of the patient to such antibiotics, and the duration of antibiotic administration. [20] Another serious and disabling side effect of aminoglycoside use is vestibular ototoxicity. [19]
Common side effects include nausea, vomiting, headaches, and diarrhea. [3] Severe allergic reactions are rare. [3] Liver problems have been reported. [3] It may cause harm if taken during pregnancy. [3] It is in the macrolide class and works by slowing down bacterial protein synthesis. [3]
Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides. Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin , teicoplanin , telavancin , ramoplanin and decaplanin, corbomycin , complestatin and the antitumor antibiotic ...
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