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  2. 3D cell culture - Wikipedia

    en.wikipedia.org/wiki/3D_cell_culture

    A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g. a Petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. [1]

  3. Swiss-model - Wikipedia

    en.wikipedia.org/wiki/Swiss-model

    The Swiss-model Workspace integrates programs and databases required for protein structure prediction and modelling in a web-based workspace. Depending on the complexity of the modelling task, different modes of use can be applied, in which the user has different levels of control over individual modelling steps: automated mode, alignment mode, and project mode.

  4. In vitro - Wikipedia

    en.wikipedia.org/wiki/In_vitro

    In vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes , and microtiter ...

  5. Cell-free protein array - Wikipedia

    en.wikipedia.org/wiki/Cell-free_protein_array

    Cell-free protein array technology produces protein microarrays by performing in vitro synthesis of the target proteins from their DNA templates. This method of synthesizing protein microarrays overcomes the many obstacles and challenges faced by traditional methods of protein array production [1] that have prevented widespread adoption of protein microarrays in proteomics.

  6. 3D modeling - Wikipedia

    en.wikipedia.org/wiki/3D_modeling

    The 3D model can be physically created using 3D printing devices that form 2D layers of the model with three-dimensional material, one layer at a time. Without a 3D model, a 3D print is not possible. 3D modeling software is a class of 3D computer graphics software used to produce 3D models. Individual programs of this class are called modeling ...

  7. Patient derived xenograft - Wikipedia

    en.wikipedia.org/wiki/Patient_derived_xenograft

    PDX models of glioblastoma (GBM) have been essential for improving our understanding of the disease both in preclinical and translational research. [29] In vitro cell culture models of glioblastoma, although valuable, can not fully replicate the complexity of the disease since there is a clear lack of the brain microenvironment and clonal ...

  8. Alternatives to animal testing - Wikipedia

    en.wikipedia.org/wiki/Alternatives_to_animal_testing

    IIVS: The Institute for In Vitro Sciences, Inc. is a non-profit research and testing laboratory dedicated to the advancement of in vitro (non-animal) methods worldwide. Founded in 1997, IIVS has worked with industry and government agencies to implement in vitro testing strategies that limit animal use while supplying key information for product ...

  9. Artificial life - Wikipedia

    en.wikipedia.org/wiki/Artificial_life

    It involves research such as the creation of synthetic DNA. The term "wet" is an extension of the term " wetware ". Efforts toward "wet" artificial life focus on engineering live minimal cells from living bacteria Mycoplasma laboratorium and in building non-living biochemical cell-like systems from scratch.

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